Prognosis of familial pancreatic cancer (FPC): A matched case analysis
نویسندگان
چکیده
منابع مشابه
Screening in Familial Pancreatic Cancer (fpc)
A. Definition of FPC A number of genetic syndromes (e.g., BRCA1/2, HNPCC, FAMMM, Peutz Jeghers syndrome) predispose kindreds to a variable but higher-thanaverage risk of developing PC (Table 1). The term familial PC (FPC) has been used for families with 2 or more first-degree relatives (FDR) with PC not associated with another described familial hereditary cancer syndrome. In this paper the ter...
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15 صفحه اولFamilial Pancreatic Cancer
Pancreatic cancer's high mortality rate equates closely with its incidence, thereby showing the need for development of biomarkers of its increased risk and a better understanding of its genetics, so that high-risk patients can be better targeted for screening and early potential lifesaving diagnosis. Its phenotypic and genotypic heterogeneity is extensive and requires careful scrutiny of its p...
متن کاملDoes pregnancy-associated breast cancer imply a worse prognosis? A matched case-case study.
BACKGROUND Significant controversy exists in the literature regarding the role of pregnancy in the prognosis of breast cancer. We designed a matched case-case study, matching pregnancy-associated breast cancer (PABC) cases with breast cancer cases for stage, age, and year of diagnosis. PATIENTS AND METHODS 39 consecutive cases of PABC were matched with 39 premenopausal cases of breast cancer....
متن کاملProspective risk of pancreatic cancer in familial pancreatic cancer kindreds.
Individuals with a family history of pancreatic cancer have an increased risk of developing pancreatic cancer. Quantification of this risk provides a rational basis for cancer risk counseling and for screening for early pancreatic cancer. In a prospective registry-based study, we estimated the risk of pancreatic cancer in individuals with a family history of pancreatic cancer. Standardized inci...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2017
ISSN: 0923-7534
DOI: 10.1093/annonc/mdx369.115